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Cumulative incidence was calculated using the Kaplan-Meier estimator method. Main Outcomes and Measures Incident SARS-CoV-2 infection, defined as a polymerase chain reaction (PCR)–positive nasopharyngeal swab regardless of reason for PCR testing or presence of symptoms. A total of 1 531 736 individuals vaccinated with either vaccine between December 21, 2020, and September 19, 2021, were followed up beginning 14 days after receiving the second dose until September 19, 2021.Įxposures Prior SARS-CoV-2 infection and COVID-19 vaccination. Objective To assess protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 infection.ĭesign, Setting, and Participants Matched-cohort studies in Qatar for the BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) vaccines. Importance The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly understood. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.Clark Files, MD David N. Hager, MD, PhD Arber Shehu, MD Matthew E. Prekker, MD, MPH Heidi L. Erickson, MD Matthew C. Exline, MD, MPH Michelle N. Gong, MD Amira Mohamed, MD Daniel J. Henning, MD, MPH Jay S. Steingrub, MD Ithan D. Peltan, MD, MSc Samuel M. Brown, MD, MS Emily T. Martin, PhD Arnold S. Monto, MD Akram Khan, MD Catherine L. Hough, MD Laurence W. Busse, MD Caitlin C. ten Lohuis, ACNP-BC Abhijit Duggal, MD Jennifer G. Wilson, MD Alexandra June Gordon, MD Nida Qadir, MD Steven Y. Chang, MD, PhD Christopher Mallow, MD, MHS Carolina Rivas, BS Hilary M. Babcock, MD, MPH Jennie H. Kwon, DO, MSci Natasha Halasa, MD, MPH James D. Chappell, MD, PhD Adam S. Lauring, MD, PhD Carlos G. Grijalva, MD, MPH Todd W. Rice, MD, MSci Ian D. Jones, MD William B. Stubblefield, MD, MPH Adrienne Baughman, BS Kelsey N. Womack, PhD Jillian P. Rhoads, PhD Christopher J. Lindsell, PhD Kimberly W. Hart, MA Yuwei Zhu, MD, MS Samantha M. Olson, MPH Miwako Kobayashi, MD Jennifer R. Verani, MD, MPH Manish M. Patel, MD Influenza and Other Viruses in the Acutely Ill (IVY) Network Keipp Talbot, MD, MPH Jonathan D. Casey, MD, MSci Nicholas M. Mohr, MD, MS Anne Zepeski, PharmD Nathan I. Shapiro, MD, MPH Kevin W. Gibbs, MD D.
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Mark W. Tenforde, MD, PhD Wesley H. Self, MD, MPH Katherine Adams, MPH Manjusha Gaglani, MBBS Adit A. Ginde, MD, MPH Tresa McNeal, MD Shekhar Ghamande, MD David J. Douin, MD H.